Efficacy of a dietary supplement on the molecular and clinical parameters of skin aging

Efficacy of a dietary supplement on the molecular and clinical parameters of skin aging

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INTRODUCTION: Oxidative stress, characterized by an imbalance between the production of reactive oxygen species (ROS) and antioxidant defense, seems to be the main process that bovi-shield gold fp 5 l5 worsens skin aging, and the mitochondria is an important source of ROS.There is increasing evidence that oral administration of functional nutrients can protect the skin from oxidative damage.OBJECTIVE: To evaluate the effectiveness of an oral supplement with collagen peptides and other nutrients in reducing the signs of photoaging.METHODS: In vitro studies evaluated the antioxidant and antiglycant effects under UV light, as well as the synthesis of extracellular dermal matrix components; then, a clinical trial was developed with women between 35 and 60 years old, swisse high strength magnesium powder berry for 12 weeks.Hydration (corneometry) and skin firmness (cutometry) measurements were performed.

RESULTS: The supplement showed antioxidant and antiglycant properties under the stress generated by UV radiation, as well as the ability to induce synthesis of extracellular dermal matrix elements; There was an improvement in all clinical parameters of aging.Significant improvement in hydration and firmness and elasticity were also observed.CONCLUSION: Collagen peptides and nutrients association demonstrated an effect in some mechanisms involved in the photoaging process, leading a clinical improvement.